Endocrine Abstracts

Background and aim: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder in women with reproductive age. Nodular goiter and autoimmune thyroid disease (AITD) are frequently seen endocrinological abnormalities. The aim of this study was to identify the prevalence of AITD and nodular goiter in PCOS patients and investigate whether PCOS related hormones and metabolic factors affect these thyroid disorders.Methods: Ninety-seven with ...

Introduction: Acromegaly is caused by growth hormone (GH) and insulin-like growth factor (IGF-1) excess and leads to various comorbidities. However, the association between acromegaly and thromboembolic diseases is unclear. Herein, we present a newly diagnosed acromegaly patient with massive pulmonary embolism.Case report: A 61-year-old female was hospitalized with acromegaly pre-diagnosis. She complained about extensive arthralgia and snoring. She had h...

Background and aim: In the general population, the frequency of thyroid micronodules is increasing and the prevalence of malignancy is higher in nodules at this size. The ultrasonographic features of these nodules are neither spesific nor sensitive Elastography gives information about the degree of hardness at the tissue level and provides assessment of malignancy risk of the nodule. The aim of the study was to investigate the diagnostic value of elastography in patients with ...

Background and aim: The risk for breast cancer in patients with thyroid cancer has been investigated in previous studies, and has been found to be increased. In this study we, therefore present retrospective analysis of the patients with differentiated thyroid carcinoma in respect to breast cancer and family history for breast cancer.Methods: We conducted a retrospective study involving 455 patients with a diagnosis of differentiated thyroid carcinoma be...

Aim: Cardiac rhythm abnormalities have been documented in acromegalic patients. Our aim is to evaluate atrial electromechanical delay (EMD) with tissue doppler imaging (TDI) in patients with acromegaly.Material and methods: Fourty patients with acromegaly (13 patients with remission disease and 27 patients with active disease; 22 women and 18 men; mean aged 46.1±10.3 years), and 37 age- and sex-matched healthy controls were enrolled in the study. At...

Aim: Overt hypothyroidism affects mostly women with an increased prevalence in individuals by age. Hypothyroidism is associated with accelerated atherosclerotic cardiovascular diseases, possibly caused by the higher incidence of hyperlipidemia, insulin resistance, hypertension which all are associated to hypothyroidism. Heart-type fatty acid binding protein (H-FABP) is specific for cardiomyocytes and a sensitive marker of myocardial injury. The purpose of this study is examini...

Aim: Several studies suggest a link between vitamin D and obesity. Vitamin D may play a role in obesity. Ghrelin is an orexigenic peptide which induces obesity by central and peripheral mechanisms. Administration of ghrelin promotes food intake and decreased fat utilisation in rodents. Ghrelin levels are decreased in obese individuals.The aim of this study was to evaluate the relationship between vitamin D status and ghrelin levels.Methods: All subjects ...